Best Practices for Coherence Extend

Run Proxy Servers with Local Storage Disabled

Do Not Run a Near Cache on a Proxy Server

Configure Heap NIO Space to be Equal to the Max Heap Size

Set Worker Thread Pool Sizes According to the Needs of the Application - configure a larger number of daemon (worker) threads for the proxy service

Be Careful When Making InvocationService Calls

Be Careful When Placing Collection Classes in the Cache - Use Collection Interface or wrap them in java objects

Run Multiple Proxies Instead of Increasing Thread Pool Size

Configure POF Serializers for Cache Servers

Use Node Locking Instead of Thread Locking

Detailed explaination can be found here.